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TI-2022-21850 Aliases CVE-2022-44451GHSA-jr2x-6qf6-q5mc

A use of uninitialized pointer vulnerability exists in the MSI format atom functionality…

Priority HIGH 82CWE-824Published · Updated

Key facts

Attack vector
Network
Privileges required
None
User interaction
None
Attack complexity
Low
Impact type
Code execution
Confidentiality · integrity · availability
High · High · High
Fix status
Fixed

Attack profile from CVSS 3.1 · CNA. Fix status from CNA and GitHub. Impact type from CWE-824 and the CVSS impact.

Summary

A use of uninitialized pointer vulnerability exists in the MSI format atom functionality of Open Babel 3.1.1 and master commit 530dbfa3. A specially crafted malformed file can lead to arbitrary code execution. An attacker can provide a malicious file to trigger this vulnerability.

Why it matters now

Exploitation Proof of concept CISA SSVC · not in CISA KEV
EPSS 0.00802 56th percentileScored 2026-11-07
Public exploit Yes 1 exploit referenceTagged by NVD
Fix Fixed openbabel (PyPI): 3.2.0

SSVC decision points

CISA ADP · SSVC 2.0.3

Exploitation
Poc
Automatable
Yes
Technical impact
Total

The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.

Affected products

VendorProductAffected versionsFixed inStatusSource
Open BabelOpen Babel3.1.1; master commit 530dbfa3—No fix listedCNA
—openbabel (PyPI)before 3.2.03.2.0Patch availableGHSA-jr2x-6qf6-q5mc
  • Open Babel VendorOpen Babel Affected 3.1.1; master commit 530dbfa3 Fixed in — No fix listed CNA
  • openbabel (PyPI) Vendor— Affected before 3.2.0 Fixed in 3.2.0 Patch available GHSA-jr2x-6qf6-q5mc

CPE configurations NVD · 1

CPEVersionsRoleVendor
cpe:2.3:a:openbabel:open_babel:3.1.1:*:*:*:*:*:*:*3.1.1VulnerableOpen Babel
  • cpe:2.3:a:openbabel:open_babel:3.1.1:*:*:*:*:*:*:* Versions 3.1.1 Vulnerable ·Open Babel

Remediation

  • Fix · GHSA-jr2x-6qf6-q5mc openbabel (PyPI) Fixed in 3.2.0 Advisory →

Vendor assessments

Red Hat

Red Hat's page for this CVE →

Not affected: 1 product
  • Red Hat

Timeline

  1. 2026-10-02 Threatist record created from CVE-2022-44451
  2. 2026-10-03 Alias added: GHSA-jr2x-6qf6-q5mc

References

  • TI-2022-22844 Memory corruption in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-22843 Memory corruption in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-22840 Memory corruption in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-22839 Heap-based buffer overflow in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-22838 Heap-based buffer overflow in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-20883 A use of uninitialized pointer vulnerability exists in the GRO format res functionality… CVSS 3.1CRITICAL 9.8
See all 23 →

Sources