Instruments with Illumina Universal Copy Service v2.x are vulnerable due to binding to an…
Priority MEDIUM 52CWE-1327Published · Updated
Key facts
- Attack vector
- Network
- Privileges required
- None
- User interaction
- None
- Attack complexity
- Low
- Impact type
- —
- Confidentiality · integrity · availability
- High · High · High
- Fix status
- No fix listed
Attack profile from CVSS 3.1 · CNA. Fix status from CNA.
Summary
Instruments with Illumina Universal Copy Service v2.x are vulnerable due to binding to an unrestricted IP address. An unauthenticated malicious actor could use UCS to listen on all IP addresses, including those capable of accepting remote communications.
Why it matters now
Exploitation None reported CISA SSVC · not in CISA KEV
EPSS 0.01812 78th percentileScored 2026-11-07
Fix No fix listed No fixed version in the sources yet
SSVC decision points
CISA ADP · SSVC 2.0.3
- Exploitation
- None
- Automatable
- Yes
- Technical impact
- Total
The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.
Affected products
| Vendor | Product | Affected versions | Fixed in | Status | Source |
|---|---|---|---|---|---|
| Illumina | iScan Control Software | 4.0.0; 4.0.5 | — | No fix listed | CNA |
| Illumina | MiniSeq Control Software | 2.0 | — | No fix listed | CNA |
| Illumina | iSeq 100 | All versions | — | No fix listed | CNA |
| Illumina | MiSeq Control Software | 4.0 (RUO Mode) | — | No fix listed | CNA |
| Illumina | MiSeqDx Operating Software | 4.0.1 | — | No fix listed | CNA |
| Illumina | NextSeq 500/550 Control Software | 4.0 | — | No fix listed | CNA |
| Illumina | NextSeq 550Dx Control Software | 4.0 (RUO Mode) | — | No fix listed | CNA |
| Illumina | NextSeq 550Dx Operating Software | 1.0.0 – 1.3.1; 1.3.3 | — | No fix listed | CNA |
| Illumina | NextSeq 1000/2000 Control Software | up to 1.4.1 | — | No fix listed | CNA |
| Illumina | NovaSeq 6000 Control Software | up to 1.7 | — | No fix listed | CNA |
| Illumina | NovaSeq Control Software | 1.8 | — | No fix listed | CNA |
- iScan Control Software VendorIllumina Affected 4.0.0; 4.0.5 Fixed in — No fix listed CNA
- MiniSeq Control Software VendorIllumina Affected 2.0 Fixed in — No fix listed CNA
- iSeq 100 VendorIllumina Affected All versions Fixed in — No fix listed CNA
- MiSeq Control Software VendorIllumina Affected 4.0 (RUO Mode) Fixed in — No fix listed CNA
- MiSeqDx Operating Software VendorIllumina Affected 4.0.1 Fixed in — No fix listed CNA
- NextSeq 500/550 Control Software VendorIllumina Affected 4.0 Fixed in — No fix listed CNA
- NextSeq 550Dx Control Software VendorIllumina Affected 4.0 (RUO Mode) Fixed in — No fix listed CNA
- NextSeq 550Dx Operating Software VendorIllumina Affected 1.0.0 – 1.3.1; 1.3.3 Fixed in — No fix listed CNA
- NextSeq 1000/2000 Control Software VendorIllumina Affected up to 1.4.1 Fixed in — No fix listed CNA
- NovaSeq 6000 Control Software VendorIllumina Affected up to 1.7 Fixed in — No fix listed CNA
- NovaSeq Control Software VendorIllumina Affected 1.8 Fixed in — No fix listed CNA
CPE configurations NVD · 26
| CPE | Versions | Role | Vendor |
|---|---|---|---|
| cpe:2.3:o:illumina:iscan_firmware:4.0.0:*:*:*:*:*:*:* | 4.0.0 | Vulnerable | Illumina |
| cpe:2.3:o:illumina:iscan_firmware:4.0.5:*:*:*:*:*:*:* | 4.0.5 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:iscan:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:iseq_100_firmware:*:*:*:*:*:*:*:* | all versions | Vulnerable | Illumina |
| cpe:2.3:h:illumina:iseq_100:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:miniseq_firmware:*:*:*:*:*:*:*:* | 2.0 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:miniseq:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:miseq_firmware:*:*:*:*:*:*:*:* | 4.0 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:miseq:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:miseqdx_firmware:*:*:*:*:-:*:*:* | 4.0.1 | Vulnerable | Illumina |
- cpe:2.3:o:illumina:iscan_firmware:4.0.0:*:*:*:*:*:*:* Versions 4.0.0 Vulnerable ·Illumina
- cpe:2.3:o:illumina:iscan_firmware:4.0.5:*:*:*:*:*:*:* Versions 4.0.5 Vulnerable ·Illumina
- cpe:2.3:h:illumina:iscan:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:iseq_100_firmware:*:*:*:*:*:*:*:* Versions all versions Vulnerable ·Illumina
- cpe:2.3:h:illumina:iseq_100:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:miniseq_firmware:*:*:*:*:*:*:*:* Versions 2.0 Vulnerable ·Illumina
- cpe:2.3:h:illumina:miniseq:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:miseq_firmware:*:*:*:*:*:*:*:* Versions 4.0 Vulnerable ·Illumina
- cpe:2.3:h:illumina:miseq:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:miseqdx_firmware:*:*:*:*:-:*:*:* Versions 4.0.1 Vulnerable ·Illumina
Show 16 more CPE
| CPE | Versions | Role | Vendor |
|---|---|---|---|
| cpe:2.3:o:illumina:miseqdx_firmware:4.0:*:*:*:ruo:*:*:* | 4.0 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:miseqdx:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:nextseq_500_firmware:4.0:*:*:*:*:*:*:* | 4.0 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:nextseq_500:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:nextseq_550_firmware:4.0:*:*:*:*:*:*:* | 4.0 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:nextseq_550:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:nextseq_550dx_firmware:*:*:*:*:-:*:*:* | 1.0.0 – 1.3.1; 1.3.3 | Vulnerable | Illumina |
| cpe:2.3:o:illumina:nextseq_550dx_firmware:4.0:*:*:*:ruo:*:*:* | 4.0 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:nextseq_550dx:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:nextseq_1000_firmware:1.4.1:*:*:*:*:*:*:* | 1.4.1 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:nextseq_1000:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:nextseq_2000_firmware:1.4.1:*:*:*:*:*:*:* | 1.4.1 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:nextseq_2000:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:o:illumina:novaseq_6000_firmware:*:*:*:*:*:*:*:* | up to 1.7 | Vulnerable | Illumina |
| cpe:2.3:o:illumina:novaseq_6000_firmware:1.8:*:*:*:*:*:*:* | 1.8 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:novaseq_6000:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
- cpe:2.3:o:illumina:miseqdx_firmware:4.0:*:*:*:ruo:*:*:* Versions 4.0 Vulnerable ·Illumina
- cpe:2.3:h:illumina:miseqdx:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:nextseq_500_firmware:4.0:*:*:*:*:*:*:* Versions 4.0 Vulnerable ·Illumina
- cpe:2.3:h:illumina:nextseq_500:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:nextseq_550_firmware:4.0:*:*:*:*:*:*:* Versions 4.0 Vulnerable ·Illumina
- cpe:2.3:h:illumina:nextseq_550:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:nextseq_550dx_firmware:*:*:*:*:-:*:*:* Versions 1.0.0 – 1.3.1; 1.3.3 Vulnerable ·Illumina
- cpe:2.3:o:illumina:nextseq_550dx_firmware:4.0:*:*:*:ruo:*:*:* Versions 4.0 Vulnerable ·Illumina
- cpe:2.3:h:illumina:nextseq_550dx:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:nextseq_1000_firmware:1.4.1:*:*:*:*:*:*:* Versions 1.4.1 Vulnerable ·Illumina
- cpe:2.3:h:illumina:nextseq_1000:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:nextseq_2000_firmware:1.4.1:*:*:*:*:*:*:* Versions 1.4.1 Vulnerable ·Illumina
- cpe:2.3:h:illumina:nextseq_2000:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:o:illumina:novaseq_6000_firmware:*:*:*:*:*:*:*:* Versions up to 1.7 Vulnerable ·Illumina
- cpe:2.3:o:illumina:novaseq_6000_firmware:1.8:*:*:*:*:*:*:* Versions 1.8 Vulnerable ·Illumina
- cpe:2.3:h:illumina:novaseq_6000:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
Remediation
No fixed version listed by the sources yet.
Fixed in the same release
Records fixed by the same vendor advisory or release, as the CNA lists them.
- Advisory ·
Illumina MiSeq Control Software, MiSeqDx Operating Software and 9 more products — support.illumina.com/downloads/illumina-universal-copy-serv…
2 records Highest priority Priority MEDIUM 2 MEDIUM
Other records, highest priority first
- TI-2023-01849 Improper privilege management in Illumina iScan Control SoftwarePriority MEDIUM 45
Timeline
- 2026-10-02 Threatist record created from CVE-2023-1968
- 2026-10-03 Alias added: GHSA-cpwh-2ghx-4jvr
References
More Illumina Iscan Firmware vulnerabilities
- TI-2023-01849 Improper privilege management in Illumina iScan Control Software CVSS 3.1CRITICAL 9.8
Sources
- CVE-2023-1968 · CVE Program
- CVE-2023-1968 · NVD
- FIRST EPSS
- GHSA-cpwh-2ghx-4jvr · GitHub Advisory Database · CC BY 4.0
This product uses the NVD API but is not endorsed or certified by the NVD. Sources and licences