Read the docs
TI-2025-11838 Aliases CVE-2025-12921GHSA-jxxq-v434-pmg5

OpenClinica Community Edition CRF Data Import ImportCRFData xml injection

Priority MEDIUM 57CWE-74Published · Updated

Key facts

Attack vector
Network
Privileges required
Low
User interaction
None
Attack complexity
Low
Attack requirements
None
Impact type
—
Confidentiality · integrity · availability
Low · None · None
Fix status
No fix listed

Attack profile from CVSS 4.0 · CNA. Fix status from CNA.

Summary

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

Why it matters now

Exploitation Proof of concept CISA SSVC · not in CISA KEV
EPSS 0.00574 47th percentileScored 2026-11-07
Public exploit Yes 2 exploit referencesTagged by NVD and the CNA
Fix No fix listed No fixed version in the sources yet

SSVC decision points

CISA ADP · SSVC 2.0.3

Exploitation
Poc
Automatable
No
Technical impact
Partial

The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.

Affected products

VendorProductAffected versionsFixed inStatusSource
OpenClinicaCommunity Edition3.0; 3.1; 3.2; 3.3; 3.4; 3.5; 3.6; 3.7; 3.8; 3.9; 3.10; 3.11; 3.12; 3.12.0; 3.12.1; 3.12.2; 3.13—No fix listedCNA
  • Community Edition VendorOpenClinica Affected 3.0; 3.1; 3.2; 3.3; 3.4; 3.5; 3.6; 3.7; 3.8; 3.9; 3.10; 3.11; 3.12; 3.12.0; 3.12.1; 3.12.2; 3.13 Fixed in — No fix listed CNA

CPE configurations NVD · 2

CPEVersionsRoleVendor
cpe:2.3:a:openclinica:openclinica:3.12.2:*:*:*:community:*:*:*3.12.2VulnerableOpenClinica
cpe:2.3:a:openclinica:openclinica:3.13:*:*:*:community:*:*:*3.13VulnerableOpenClinica
  • cpe:2.3:a:openclinica:openclinica:3.12.2:*:*:*:community:*:*:* Versions 3.12.2 Vulnerable ·OpenClinica
  • cpe:2.3:a:openclinica:openclinica:3.13:*:*:*:community:*:*:* Versions 3.13 Vulnerable ·OpenClinica

Remediation

No fixed version listed by the sources yet.

Timeline

  1. 2026-10-02 Threatist record created from CVE-2025-12921
  2. 2026-10-03 Alias added: GHSA-jxxq-v434-pmg5

References

  • TI-2022-08643 Path Traversal in OpenClinica CVSS 3.1CRITICAL 9.8
  • TI-2025-11839 OpenClinica Community Edition CRF Data Import ImportCRFData path traversal CVSS 4.0MEDIUM 5.3
  • TI-2022-08644 Improper Neutralization of Special Elements used in an SQL Command ('SQL Injection') in OpenClinica CVSS 3.1CRITICAL 9.8

Sources