Bio.Entrez in Biopython through 186 allows doctype XXE.
Priority LOW 22CWE-611Published · Updated
Key facts
- Attack vector
- Network
- Privileges required
- Low
- User interaction
- None
- Attack complexity
- High
- Impact type
- —
- Confidentiality · integrity · availability
- Low · None · Low
- Fix status
- No fix listed
Attack profile from CVSS 3.1 · CNA. Fix status from CNA and GitHub.
Summary
Bio.Entrez in Biopython through 186 allows doctype XXE.
Why it matters now
Exploitation None reported CISA SSVC · not in CISA KEV
EPSS 0.00316 24th percentileScored 2026-11-07
Fix No fix listed No fixed version in the sources yet
SSVC decision points
CISA ADP · SSVC 2.0.3
- Exploitation
- None
- Automatable
- No
- Technical impact
- Partial
The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.
Affected products
| Vendor | Product | Affected versions | Fixed in | Status | Source |
|---|---|---|---|---|---|
| Biopython | Biopython | up to 186 | — | No fix listed | CNA |
| — | biopython (PyPI) | up to 1.86 | — | No fix listed | GHSA-x3vf-39hj-gxr4 |
- Biopython VendorBiopython Affected up to 186 Fixed in — No fix listed CNA
- biopython (PyPI) Vendor— Affected up to 1.86 Fixed in — No fix listed GHSA-x3vf-39hj-gxr4
Remediation
No fixed version listed by the sources yet.
Vendor assessments
Timeline
- 2026-10-02 Threatist record created from CVE-2025-68463
- 2026-10-03 Alias added: GHSA-x3vf-39hj-gxr4
References
Other 7
- https://github.com/biopython/biopython/issues/5109
- https://pypi.org/project/biopython/1.87/
- https://github.com/biopython/biopython/blob/master/NEWS.rst
- https://github.com/biopython/biopython/commit/736c96f37b190732ecca9da80ad0cb9d4967214d
- https://github.com/biopython/biopython
- https://pypi.org/project/biopython/1.87
- http://www.openwall.com/lists/oss-security/2026/05/08/16
Sources
- CVE-2025-68463 · CVE Program
- CVE-2025-68463 · NVD
- FIRST EPSS
- GHSA-x3vf-39hj-gxr4 · GitHub Advisory Database · CC BY 4.0
- CVE-2025-68463 · Red Hat security data · CC BY 4.0
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