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TI-2025-10067 Aliases CVE-2025-10996GHSA-j35x-w4gj-pf7w

Open Babel smilesformat.cpp ParseSmiles heap-based overflow

Priority MEDIUM 55CWE-119Published · Updated

Key facts

Attack vector
Local
Privileges required
Low
User interaction
None
Attack complexity
Low
Attack requirements
None
Impact type
—
Confidentiality · integrity · availability
Low · Low · Low
Fix status
Fixed

Attack profile from CVSS 4.0 · CNA. Fix status from CNA and GitHub.

Summary

A vulnerability was detected in Open Babel up to 3.1.1. This issue affects the function OBSmilesParser::ParseSmiles of the file /src/formats/smilesformat.cpp. Performing manipulation results in heap-based buffer overflow. The attack needs to be approached locally. The exploit is now public and may be used.

Why it matters now

Exploitation Proof of concept CISA SSVC · not in CISA KEV
EPSS 0.00286 21st percentileScored 2026-11-07
Public exploit Yes 2 exploit referencesTagged by NVD and the CNA
Fix Fixed openbabel (PyPI): 3.2.0

SSVC decision points

CISA ADP · SSVC 2.0.3

Exploitation
Poc
Automatable
No
Technical impact
Partial

The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.

Affected products

VendorProductAffected versionsFixed inStatusSource
—Open Babel3.1.0; 3.1.1—No fix listedCNA
—openbabel (PyPI)before 3.2.03.2.0Patch availableGHSA-j35x-w4gj-pf7w
  • Open Babel Vendor— Affected 3.1.0; 3.1.1 Fixed in — No fix listed CNA
  • openbabel (PyPI) Vendor— Affected before 3.2.0 Fixed in 3.2.0 Patch available GHSA-j35x-w4gj-pf7w

CPE configurations NVD · 1

CPEVersionsRoleVendor
cpe:2.3:a:openbabel:open_babel:*:*:*:*:*:*:*:*up to 3.1.1VulnerableOpen Babel
  • cpe:2.3:a:openbabel:open_babel:*:*:*:*:*:*:*:* Versions up to 3.1.1 Vulnerable ·Open Babel

Remediation

  • Fix · GHSA-j35x-w4gj-pf7w openbabel (PyPI) Fixed in 3.2.0 Advisory →

Vendor assessments

Red Hat

Red Hat's page for this CVE →

Not affected: 1 product
  • Red Hat

Timeline

  1. 2026-10-02 Threatist record created from CVE-2025-10996
  2. 2026-10-03 Alias added: GHSA-j35x-w4gj-pf7w

References

  • TI-2022-22844 Memory corruption in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-22843 Memory corruption in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-22840 Memory corruption in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-22839 Heap-based buffer overflow in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-22838 Heap-based buffer overflow in Open Babel CVSS 3.1CRITICAL 9.8
  • TI-2022-21850 A use of uninitialized pointer vulnerability exists in the MSI format atom functionality… CVSS 3.1CRITICAL 9.8
See all 23 →

Sources