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TI-2025-36415 Aliases CVE-2025-58757GHSA-p8cm-mm2v-gwjm

MONAI's unsafe use of Pickle deserialization may lead to RCE

Priority HIGH 73CWE-502Published · Updated

Key facts

Attack vector
Network
Privileges required
None
User interaction
Required
Attack complexity
Low
Impact type
Code execution
Confidentiality · integrity · availability
High · High · High
Fix status
Fixed

Attack profile from CVSS 3.1 · CNA. Fix status from CNA and GitHub. Impact type from CWE-502.

Summary

MONAI (Medical Open Network for AI) is an AI toolkit for health care imaging. In versions up to and including 1.5.0, the `pickle_operations` function in `monai/data/utils.py` automatically handles dictionary key-value pairs ending with a specific suffix and deserializes them using `pickle.loads()` . This function also lacks any security measures. The deserialization may lead to code execution. As of time of publication, no known fixed versions are available.

Why it matters now

Exploitation Proof of concept CISA SSVC · not in CISA KEV
EPSS 0.00645 51st percentileScored 2026-11-07
Public exploit Yes 1 exploit referenceTagged by NVD
Fix Fixed monai (PyPI): 1.5.1

SSVC decision points

CISA ADP · SSVC 2.0.3

Exploitation
Poc
Automatable
No
Technical impact
Total

The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.

Affected products

VendorProductAffected versionsFixed inStatusSource
Project-MONAIMONAIup to 1.5.0—No fix listedCNA
—monai (PyPI)before 1.5.11.5.1Patch availableGHSA-p8cm-mm2v-gwjm
  • MONAI VendorProject-MONAI Affected up to 1.5.0 Fixed in — No fix listed CNA
  • monai (PyPI) Vendor— Affected before 1.5.1 Fixed in 1.5.1 Patch available GHSA-p8cm-mm2v-gwjm

CPE configurations NVD · 1

CPEVersionsRoleVendor
cpe:2.3:a:monai:medical_open_network_for_ai:*:*:*:*:*:*:*:*up to 1.5.0VulnerableMonai
  • cpe:2.3:a:monai:medical_open_network_for_ai:*:*:*:*:*:*:*:* Versions up to 1.5.0 Vulnerable ·Monai

Remediation

  • Fix · GHSA-p8cm-mm2v-gwjm monai (PyPI) Fixed in 1.5.1 Advisory →

Timeline

  1. 2026-10-02 Threatist record created from CVE-2025-58757
  2. 2026-10-03 Alias added: GHSA-p8cm-mm2v-gwjm
  3. 2026-10-20 EPSS moved to the 50th–90th percentile

References

Exploit 1

Advisory 1

Other 4

  • TI-2026-85662 MONAI accepts non-finite DICOM geometry values, corrupting inference CVSS 3.1CRITICAL 9.3
  • TI-2026-64984 MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization CVSS 4.0HIGH 8.8
  • TI-2026-83080 Remote code execution in MONAI Auto3DSeg algo_from_json() CVSS 4.0HIGH 8.5
  • TI-2026-64983 MONAI before 1.6.0 Remote Code Execution via NumpyReader CVSS 4.0HIGH 8.5
  • TI-2026-64982 MONAI before 1.6.0 OS Command Injection via dataset_name_or_id CVSS 4.0HIGH 8.6
  • TI-2026-64981 MONAI before 1.6.0 Remote Code Execution via algo_from_pickle CVSS 4.0HIGH 8.5
See all 16 →

Sources

This product uses the NVD API but is not endorsed or certified by the NVD. Sources and licences