OpenSlide: openslide_read_region() returns uninitialized memory with libtiff 4.7.1
Key facts
- Attack vector
- Network
- Privileges required
- Low
- User interaction
- None
- Attack complexity
- Low
- Attack requirements
- None
- Impact type
- Information disclosure
- Confidentiality · integrity · availability
- Low · None · None
- Fix status
- Fixed
Attack profile from CVSS 4.0 · CNA. Fix status from CNA. Impact type from CWE-908 and the CVSS impact.
Summary
OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.
Why it matters now
SSVC decision points
CISA ADP · SSVC 2.0.3
- Exploitation
- None
- Automatable
- No
- Technical impact
- Partial
The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.
Affected products
Remediation
- Fix · CNA openslide (openslide) Fixed in 4.0.1
Vendor assessments
Timeline
- 2026-10-02 Threatist record created from CVE-2026-54604
- 2026-11-03 Affected versions changed · Red Hat
- 2026-11-03 CVSS score added · Red Hat
References
Other 7
- https://github.com/openslide/openslide/security/advisories/GHSA-f734-jv98-5677
- https://github.com/openslide/openslide-bin/issues/433
- https://github.com/openslide/openslide-bin/pull/436
- https://github.com/openslide/openslide/pull/706
- https://github.com/openslide/openslide/commit/a4f0fb0ec462edcea97ff22288f606ac6cd370f5
- https://github.com/openslide/openslide/releases/tag/v4.0.1
- https://gitlab.com/libtiff/libtiff/-/work_items/791
More openslide vulnerabilities
- TI-2026-74914 Out-of-bounds read in OpenSlide MIRAX reader crashes apps CVSS 4.0MEDIUM 6.9
- TI-2026-36233 OpenSlide: Arbitrary memory write with crafted Ventana BIF file CVSS 4.0HIGH 7.7
Sources
- CVE-2026-54604 · CVE Program
- CVE-2026-54604 · NVD
- FIRST EPSS
- CVE-2026-54604 · Red Hat security data · CC BY 4.0
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