3.2.1 EXECUTION WITH UNNECESSARY PRIVILEGES CWE-250
Priority MEDIUM 52CWE-250Published · Updated
Key facts
- Attack vector
- Network
- Privileges required
- None
- User interaction
- None
- Attack complexity
- Low
- Impact type
- Privilege escalation
- Confidentiality · integrity · availability
- High · High · High
- Fix status
- No fix listed
Attack profile from CVSS 3.1 · CNA. Fix status from CNA. Impact type from CWE-250.
Summary
LRM utilizes elevated privileges. An unauthenticated malicious actor can upload and execute code remotely at the operating system level, which can allow an attacker to change settings, configurations, software, or access sensitive data on the affected produc. An attacker could also exploit this vulnerability to access APIs not intended for general use and interact through the network.
Why it matters now
Exploitation None reported CISA SSVC · not in CISA KEV
EPSS 0.01822 78th percentileScored 2026-11-07
Fix No fix listed No fixed version in the sources yet
SSVC decision points
CISA ADP · SSVC 2.0.3
- Exploitation
- None
- Automatable
- Yes
- Technical impact
- Total
The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.
Affected products
| Vendor | Product | Affected versions | Fixed in | Status | Source |
|---|---|---|---|---|---|
| Illumina | NextSeq 550Dx | LRM Versions 1.3 to 3.1 | — | No fix listed | CNA |
| Illumina | MiSeq Dx | LRM Versions 1.3 to 3.1 | — | No fix listed | CNA |
| Illumina | NextSeq 500 Instrument | LRM Versions 1.3 to 3.1 | — | No fix listed | CNA |
| Illumina | NextSeq 550 Instrument | LRM Versions 1.3 to 3.1 | — | No fix listed | CNA |
| Illumina | MiSeq Instrument | LRM Versions 1.3 to 3.1 | — | No fix listed | CNA |
| Illumina | iSeq 100 Instrument | LRM Versions 1.3 to 3.1 | — | No fix listed | CNA |
| Illumina | MiniSeq Instrument | LRM Versions 1.3 to 3.1 | — | No fix listed | CNA |
- NextSeq 550Dx VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
- MiSeq Dx VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
- NextSeq 500 Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
- NextSeq 550 Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
- MiSeq Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
- iSeq 100 Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
- MiniSeq Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
CPE configurations NVD · 8
| CPE | Versions | Role | Vendor |
|---|---|---|---|
| cpe:2.3:a:illumina:local_run_manager:*:*:*:*:*:*:*:* | 1.3 – 3.1 | Vulnerable | Illumina |
| cpe:2.3:h:illumina:iseq_100:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:h:illumina:miniseq:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:h:illumina:miseq:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:h:illumina:miseq_dx:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:h:illumina:nextseq_500:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:h:illumina:nextseq_550:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
| cpe:2.3:h:illumina:nextseq_550dx:-:*:*:*:*:*:*:* | not specified by NVD | Running on | Illumina |
- cpe:2.3:a:illumina:local_run_manager:*:*:*:*:*:*:*:* Versions 1.3 – 3.1 Vulnerable ·Illumina
- cpe:2.3:h:illumina:iseq_100:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:h:illumina:miniseq:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:h:illumina:miseq:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:h:illumina:miseq_dx:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:h:illumina:nextseq_500:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:h:illumina:nextseq_550:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
- cpe:2.3:h:illumina:nextseq_550dx:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
Remediation
No fixed version listed by the sources yet.
Timeline
- 2026-10-02 Threatist record created from CVE-2022-1517
- 2026-10-03 Alias added: GHSA-xwwx-p8gv-wf69
References
More Illumina Local Run Manager vulnerabilities
- TI-2022-01392 Unrestricted file upload in Illumina NextSeq 550Dx CVSS 3.1CRITICAL 10.0
- TI-2022-01391 3.2.2 IMPROPER LIMITATION OF A PATHNAME TO A RESTRICTED DIRECTORY ('PATH TRAVERSAL') CWE-22 CVSS 3.1CRITICAL 10.0
- TI-2022-01394 3.2.4 IMPROPER ACCESS CONTROL CWE-284 CVSS 3.1CRITICAL 9.1
- TI-2022-01397 3.2.5 CLEARTEXT TRANSMISSION OF SENSITIVE INFORMATION CWE-319 CVSS 3.1HIGH 7.4
Sources
- CVE-2022-1517 · CVE Program
- CVE-2022-1517 · NVD
- FIRST EPSS
- GHSA-xwwx-p8gv-wf69 · GitHub Advisory Database · CC BY 4.0
This product uses the NVD API but is not endorsed or certified by the NVD. Sources and licences