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TI-2022-01391 Aliases CVE-2022-1518GHSA-gf32-9r48-vxjm

3.2.2 IMPROPER LIMITATION OF A PATHNAME TO A RESTRICTED DIRECTORY ('PATH TRAVERSAL') CWE-22

Priority MEDIUM 52CWE-22Published · Updated

Key facts

Attack vector
Network
Privileges required
None
User interaction
None
Attack complexity
Low
Impact type
—
Confidentiality · integrity · availability
High · High · High
Fix status
No fix listed

Attack profile from CVSS 3.1 · CNA. Fix status from CNA.

Summary

LRM contains a directory traversal vulnerability that can allow a malicious actor to upload outside the intended directory structure.

Why it matters now

Exploitation None reported CISA SSVC · not in CISA KEV
EPSS 0.01669 76th percentileScored 2026-11-07
Fix No fix listed No fixed version in the sources yet

SSVC decision points

CISA ADP · SSVC 2.0.3

Exploitation
None
Automatable
Yes
Technical impact
Total

The decision (Track, Attend, Act) also depends on your mission and well-being impact; see CISA's SSVC guide.

Affected products

VendorProductAffected versionsFixed inStatusSource
IlluminaNextSeq 550DxLRM Versions 1.3 to 3.1—No fix listedCNA
IlluminaMiSeq DxLRM Versions 1.3 to 3.1—No fix listedCNA
IlluminaNextSeq 500 InstrumentLRM Versions 1.3 to 3.1—No fix listedCNA
IlluminaNextSeq 550 InstrumentLRM Versions 1.3 to 3.1—No fix listedCNA
IlluminaMiSeq InstrumentLRM Versions 1.3 to 3.1—No fix listedCNA
IlluminaiSeq 100 InstrumentLRM Versions 1.3 to 3.1—No fix listedCNA
IlluminaMiniSeq InstrumentLRM Versions 1.3 to 3.1—No fix listedCNA
  • NextSeq 550Dx VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
  • MiSeq Dx VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
  • NextSeq 500 Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
  • NextSeq 550 Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
  • MiSeq Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
  • iSeq 100 Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA
  • MiniSeq Instrument VendorIllumina Affected LRM Versions 1.3 to 3.1 Fixed in — No fix listed CNA

CPE configurations NVD · 8

CPEVersionsRoleVendor
cpe:2.3:a:illumina:local_run_manager:*:*:*:*:*:*:*:*1.3 – 3.1VulnerableIllumina
cpe:2.3:h:illumina:iseq_100:-:*:*:*:*:*:*:*not specified by NVDRunning onIllumina
cpe:2.3:h:illumina:miniseq:-:*:*:*:*:*:*:*not specified by NVDRunning onIllumina
cpe:2.3:h:illumina:miseq:-:*:*:*:*:*:*:*not specified by NVDRunning onIllumina
cpe:2.3:h:illumina:miseq_dx:-:*:*:*:*:*:*:*not specified by NVDRunning onIllumina
cpe:2.3:h:illumina:nextseq_500:-:*:*:*:*:*:*:*not specified by NVDRunning onIllumina
cpe:2.3:h:illumina:nextseq_550:-:*:*:*:*:*:*:*not specified by NVDRunning onIllumina
cpe:2.3:h:illumina:nextseq_550dx:-:*:*:*:*:*:*:*not specified by NVDRunning onIllumina
  • cpe:2.3:a:illumina:local_run_manager:*:*:*:*:*:*:*:* Versions 1.3 – 3.1 Vulnerable ·Illumina
  • cpe:2.3:h:illumina:iseq_100:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
  • cpe:2.3:h:illumina:miniseq:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
  • cpe:2.3:h:illumina:miseq:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
  • cpe:2.3:h:illumina:miseq_dx:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
  • cpe:2.3:h:illumina:nextseq_500:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
  • cpe:2.3:h:illumina:nextseq_550:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina
  • cpe:2.3:h:illumina:nextseq_550dx:-:*:*:*:*:*:*:* Versions not specified by NVD Running on ·Illumina

Remediation

No fixed version listed by the sources yet.

Timeline

  1. 2026-10-02 Threatist record created from CVE-2022-1518
  2. 2026-10-03 Alias added: GHSA-gf32-9r48-vxjm

References

  • TI-2022-01392 Unrestricted file upload in Illumina NextSeq 550Dx CVSS 3.1CRITICAL 10.0
  • TI-2022-01390 3.2.1 EXECUTION WITH UNNECESSARY PRIVILEGES CWE-250 CVSS 3.1CRITICAL 10.0
  • TI-2022-01394 3.2.4 IMPROPER ACCESS CONTROL CWE-284 CVSS 3.1CRITICAL 9.1
  • TI-2022-01397 3.2.5 CLEARTEXT TRANSMISSION OF SENSITIVE INFORMATION CWE-319 CVSS 3.1HIGH 7.4

Sources